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閲覧数:90
ID 39445744
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本文 TohoJMed003001041.pdf
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タイトル Left Ventricular Diastolic Dysfunction is an Independent Predictor of Late Recurrence After Successful Radiofrequency Catheter Ablation of Persistent or Paroxysmal Atrial Fibrillation
別タイトル
著者
Hideki, Koike
Department of Cardiovascular Medicine, Toho University Graduate School of Medicine,Division of Cardiovascular Medicine (Omori), Department of Internal Medicine, School of Medicine, Faculty of Medicine, Toho University
[役割]Author
Tadashi, Fujino
Division of Cardiovascular Medicine (Omori), Department of Internal Medicine, School of Medicine, Faculty of Medicine, Toho University
[役割]Author
Makiko, Koike
Division of Cardiovascular Medicine (Omori), Department of Internal Medicine, School of Medicine, Faculty of Medicine, Toho University
[役割]Author
Masaya, Shinohara
Division of Cardiovascular Medicine (Omori), Department of Internal Medicine, School of Medicine, Faculty of Medicine, Toho University
[役割]Author
Hitomi, Yuzawa
Division of Cardiovascular Medicine (Omori), Department of Internal Medicine, School of Medicine, Faculty of Medicine, Toho University
[役割]Author
Takeya, Suzuki
Division of Cardiovascular Medicine (Omori), Department of Internal Medicine, School of Medicine, Faculty of Medicine, Toho University
[役割]Author
Shunji, Fukunaga
Division of Cardiovascular Medicine (Omori), Department of Internal Medicine, School of Medicine, Faculty of Medicine, Toho University
[役割]Author
Kenzaburo, Kobayashi
Division of Cardiovascular Medicine (Omori), Department of Internal Medicine, School of Medicine, Faculty of Medicine, Toho University
[役割]Author
Takanori, Ikeda
Division of Cardiovascular Medicine (Omori), Department of Internal Medicine, School of Medicine, Faculty of Medicine, Toho University
[役割]Author
出版地 Tokyo
出版者 The Medical Society of Toho University
形態
上位タイトル
Toho Journal of Medicine (Toho Journal of Medicine). Vol.3, No.1  (2017. 3) ,p.41- 49
識別番号
ISSN
21891990
DOI
URI
JaLCDOI info:doi/10.14994/tohojmed.2016.032
抄録 Background: Several echocardiographic parameters assessed before radiofrequency catheter ablation (RFCA) are associated with recurrence of atrial fibrillation (AF). However, data are limited on the associations of changes in these parameters and late recurrence (LR) of AF. Methods: This study investigated data from 198 consecutive patients with AF (age 63.4±10.5 years; paroxysmal AF 65.7%) who successfully underwent RFCA and maintained sinus rhythm for at least 1 year after RFCA. All patients underwent echocardiography at baseline and at 3 months and 1 year after RFCA. We analyzed associations of LR (any recurrence later than 1 year after RFCA) with changes in echocardiographic parameters, namely, left ventricular ejection fraction, left atrial diameter (LAD), and E/A and E/e' ratios. Results: During a mean follow-up period of 29.7±11.9 months, 17 patients (8.6%) developed LR. As compared with patients who maintained sinus rhythm, patients with LR had a significantly higher LAD at 1 year after RFCA (36.5 vs 39.2 mm, respectively; p < 0.001) and a significantly higher E/e' ratio (10.6±4.1 vs 13.0±3.7, respectively; p = 0.017). Kaplan-Meier and multivariate Cox proportional hazards models revealed that an E/e' ratio >10 (hazard ratio, 4.44; 95% confidence interval, 1.269 ― 15.53; p = 0.020) and use of antiarrhythmic drugs after RFCA (hazard ratio 2.81; 95% confidence interval, 1.079 ― 7.299; p = 0.034) were significant predictors of and independently associated with LR, regardless of LAD. Conclusion: LAD significantly improved in patients who maintained sinus rhythm after RFCA; however, improved LAD was not associated with decreased risk of LR. An E/e' ratio >10 at 1 year after RFCA was significantly associated with LR.
キーワード
E/e' ratio
left atrial diameter
echocardiography
and pulmonary vein isolation
NDC
注記 Original Article
言語
eng
資源タイプ TOHO University Scholarly Publication
ジャンル Journal Article
著者版フラグ publisher
アクセス条件 東邦大学医学会
Index
/ Public / Toho Journal of Medicine / Vol.3 / No.1(p.1-49)
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