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閲覧数:104
ID 21619331
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本文 TohoJMed003001026.pdf
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URI
タイトル Use of Urinary Biomarkers for Early Diagnosis of Acute Kidney Injury After Descending Thoracic Aorta Surgery
別タイトル
著者
Takaaki, Kamada
Department of Anesthesiology, Kawasaki Saiwai Hospital,Department of Anesthesiology, Toho University Graduate School of Medicine,Department of Anesthesiology (Omori), School of Medicine, Faculty of Medicine, Toho University
[役割]Author
Ryoichi, Ochiai
Department of Anesthesiology (Omori), School of Medicine, Faculty of Medicine, Toho University
[役割]Author
出版地 Tokyo
出版者 The Medical Society of Toho University
形態
上位タイトル
Toho Journal of Medicine (Toho Journal of Medicine). Vol.3, No.1  (2017. 3) ,p.26- 33
識別番号
ISSN
21891990
DOI
URI
JaLCDOI info:doi/10.14994/tohojmed.2016.030
抄録 Background: Acute kidney injury (AKI) is a common complication after cardiovascular surgery. The incidence of AKI after cardiovascular surgery is high, which worsens outcomes. We examined the incidence of AKI after aortic surgery without circulatory arrest and the effectiveness of AKI urinary biomarkers, including liver-type fatty acid-binding protein (L-FABP) and neutrophil gelatinase-associated lipocalin (NGAL). Methods: The participants were 60 adults who underwent surgery for a descending thoracic aortic aneurysm with left heart bypass technique under general anesthesia. Urinary L-FABP and NGAL levels were measured immediately and 24 hours after surgery and compared between patients with and without AKI. Results: Twenty-one patients (35%) developed AKI. Urinary L-FABP level significantly differed between the AKI group and non-AKI group at 24 hours after surgery. In contrast, urinary NGAL was not associated with AKI. Conclusions: After replacement of the descending aorta, which can cause mild reperfusion injury, L-FABP was better than NGAL in predicting postoperative AKI.
キーワード
aortic surgery
acute kidney injury (AKI)
liver-type fatty acid-binding protein (L-FABP)
neutrophil gelatinase-associated lipocalin (NGAL)
NDC
注記 Original Article
言語
eng
資源タイプ TOHO University Scholarly Publication
ジャンル Journal Article
著者版フラグ publisher
アクセス条件 東邦大学医学会
Index
/ Public / Toho Journal of Medicine / Vol.3 / No.1(p.1-49)
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