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閲覧数:111
ID 15602954
アイテムタイプ Article
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本文 TohoJMed003001010.pdf
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タイトル Cryoprecipitate May Reduce the Need for Blood Products During Congenital Heart Surgery
別タイトル
著者
Yuzo, Katayama
Division of Cardiovascular Surgery (Omori), Department of Surgery, School of Medicine, Faculty of Medicine, Toho University
[役割]Author
出版地 Tokyo
出版者 The Medical Society of Toho University
形態
上位タイトル
Toho Journal of Medicine (Toho Journal of Medicine). Vol.3, No.1  (2017. 3) ,p.10- 16
識別番号
ISSN
21891990
DOI
URI
JaLCDOI info:doi/10.14994/tohojmed.2016.022
抄録 Background: This study assessed the effectiveness of cryoprecipitate ― a concentrated product containing coagulation factors from fresh frozen plasma ― in managing dilutional coagulopathy during congenital heart surgery. Methods: This prospective observational study included 10 consecutive patients with complex congenital heart disease, including tetralogy of Fallot, who underwent surgery involving cardiopulmonary bypass during the period from November 2014 to April 2015. The 10 patients received cryoprecipitate and cryoprecipitate-removed plasma in addition to conventional transfusion. Their results were compared with those of 10 consecutive patients with complex congenital heart disease who had undergone heart surgery during the period from January 2014 to October 2014 and received conventional transfusion alone. Results: Plasma fibrinogen concentration increased from 257 mg/dl to 892 mg/dl during the acquisition of cryoprecipitate from plasma. The average number of transfused units of fresh frozen plasma, including the cryoprecipitate source and amount of platelet concentrate transfused, were lower in patients receiving cryoprecipitate (4.5 ± 2.2 vs 6.3 ± 4.4 units, 56.3 ± 61.6 vs 135 ± 152 ml, respectively; p<0.05). Conclusions: Use of cryoprecipitate might reduce the amount of transfused blood products needed during complex congenital heart surgery under cardiopulmonary bypass.
キーワード
congenital heart surgery
blood transfusion
cryoprecipitate
NDC
注記 Original Article
言語
eng
資源タイプ TOHO University Scholarly Publication
ジャンル Journal Article
著者版フラグ publisher
アクセス条件 東邦大学医学会
Index
/ Public / Toho Journal of Medicine / Vol.3 / No.1(p.1-49)
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